What syndrome is associated with multiple odontomas and colorectal polyposis?

Gardner Syndrome is characterized by the presence of multiple odontomas along with colorectal polyposis. This genetic disorder is a variant of familial adenomatous polyposis (FAP), which predisposes individuals to develop numerous polyps in the colon, increasing the risk of colorectal cancer. In addition to colonic polyps, individuals with Gardner Syndrome often present with distinctive dental anomalies, including the formation of multiple odontomas, which are benign tumors associated with tooth development.

This syndrome is also noted for other extracolonic manifestations such as soft tissue tumors, desmoid tumors, and osteomas, further differentiating it from other syndromes listed. The association of multiple odontomas with polyposis is particularly telling, as it is a hallmark feature of Gardner Syndrome that sets it apart from conditions like Gorlin Syndrome, which is primarily linked to basal cell nevus syndrome, and does not specifically involve odontomas or colorectal polyps. Li-Fraumeni Syndrome and Turner Syndrome also do not have the same dental and gastrointestinal manifestations as Gardner Syndrome.